Day care versus inpatient management of nausea and vomiting of pregnancy: cost utility analysis of a randomised controlled trial.

10 Feb 2016

Objective

To assess the comparative cost effectiveness of day care over inpatient management of nausea and vomiting of pregnancy (NVP).

Study design

A cost utility analysis was performed using a decision analytical model in which a Markov model was constructed. The Markov model was primarily populated with data from a recently published randomised controlled trial. Which included pregnant women presenting to Cork University Maternity Hospital, a tertiary referral maternity hospital, seeking treatment for NVP. Costs and outcomes were estimated from the perspective of the Irish health service (HSE) and patients. A probabilistic sensitivity analysis, using a Monte Carlo simulation, was also performed. A Bayesian Value of Information analysis was used to estimate the value of collecting additional information.

Results

When both the healthcare provider and patient's perspective was considered, day care management of NVP remained less costly (mean €985; 95% C.I. 705–1456 vs. €3837 (2124–8466)) and more effective (9.42; 4.19–12.25 vs. 9.49; 4.32–12.39 quality adjusted life years) compared with inpatient management. The Cost Effectiveness Acceptability Curve indicates the probability that day care management is 70% more cost effective compared to inpatient management at a ceiling ratio of €45,000 per QALY, indicating little decision uncertainty. The Bayesian Value of Information analysis indicates there is value in collecting further information; the Expected Value of Perfect Information (EVPI) is estimated to be €5.4 million.

Conclusion

Day care management of NVP is cost effective compared to inpatient management.

Identifier: 
10.1016/j.ejogrb.2015.10.022
Citation for this resource: 
Murphy, A., McCarthy, F., McElroy, B., Khashan, A., Spillane, N., Marchocki, Z., Sarkar, R. and Higgins, J. (2016). Day care versus inpatient management of nausea and vomiting of pregnancy: cost utility analysis of a randomised controlled trial. European Journal of Obstetrics & Gynecology and Reproductive Biology, 197, pp.78-82.
Resource type: 

Add new comment

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
By submitting this form, you accept the Mollom privacy policy.

Subscribe to our mailing list