Publications and Reports

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E.g., 24 Nov 2017
E.g., 24 Nov 2017
10 Oct 2013

Background

Despite rapidly declining coronary heart disease (CHD) mortality rates over the last two decades, CHD mortality rates on the island of Ireland are still amongst the highest in Europe. This study aimed to use a modelling approach to

i) Estimate the potential reduction in CHD and stroke deaths by decreasing salt, trans-fat and saturated fat consumption, and by increasing fruit and vegetable (F/V) consumption in Irish adults for 2010.

ii) Assess the potential impa...

10 Oct 2013

Abstract

Background

Recent declines in CVD mortality in Ireland and other developed countries are partially attributable to favourable secular trends in blood pressure (BP). However the underlying causes of these BP trends are not well defined. In particular, the contribution of changes in the dietary and other lifestyle determinants of population BP levels is unclear. We examined changes in distribution and determinants of systolic blood pressure (SBP) in middle-aged Irish adu...

10 Oct 2013

Abstract

Background

 As a result of changes in lifestyle and increased intake of processed foods in recent years population level salt intakes have increased. However, few studies have objectively measured dietary salt intake in children, and no Irish data exists. This study aims to objectively measure total dietary salt intake in Irish children assessed by urinary sodium excretion from spot and 24 hour samples and further to assess the concordance between spot and 24hour urina...

10 Oct 2013

Abstract

Background

There is a current lack of consensus on defining metabolically healthy obesity (MHO). Limited data on dietary and lifestyle behaviours and MHO exist. This study compared the prevalence, dietary factors and lifestyle behaviours of metabolically healthy and unhealthy obese and non-obese subjects according to different metabolic health criteria.

Methods

Cross-sectional sample of 1,008 men and 1,039 women aged 45-74 years participated in the study....

11 Sep 2013

Abstract

Background The difference between a working and a non-working middle to older aged population and their lifestyle behaviours has not been investigated previously. Furthermore, the association between positive job characteristics for current older workers and the co-occurrence of positive lifestyle behaviours (PLBs) is scarcely known.

Methods We carried out a cross-sectional study on a sample of 2,047 males and females aged between 50-69 years. Data were collected on soc...

1 Jan 2013

Objective

Chronic low levels of inflammation have linked to obesity, diabetes and insulin resistance. We sought to assess the relationship between cytokine tumor necrosis factor (TNF-α) and insulin resistance in a healthy, euglycemic population.

Study Design

This is a prospective study of 564 non-diabetic mother and infant pairs. Maternal body mass index (BMI), TNF-α, glucose and insulin were measured in early pregnancy and at 28 weeks. Insulin resistance calculated by HO...

29 Aug 2012
Background High infant birth weight (macrosomia) is associated with an increase in adverse maternal and fetal outcomes. Excessive weight gain during pregnancy is an important risk factor for macrosomia in non-diabetic pregnancies. The use of qualitative methods to gain an in-depth understanding of views about weight gain during pregnancy among women whose first infant was macrosomic may provide an insight into the provision of weight management advice for pregnant women. Aim To explore views abo...

6 Feb 2012

Abstract

Objective

Fetal macrosomia is associated with an increase in adverse obstetric and neonatal outcomes, and also confers a future risk of childhood obesity. Metabolomics is the study of small molecules present in biological samples. Our objective was to determine if early pregnancy urinary metabolomic profiles could predict fetal adiposity and macrosomia.

Study Design

Fifty secundigravid women who previously delivered a macrosomic infant >4kg were recruit...

7 Aug 2011

Abstract

At no point in the life cycle is nutrition more important than before and during pregnancy. Diet is a major environmental factor influencing the development of the embryo and fetus, while maintaining maternal health. Impaired development in utero may “programme” the fetus for developing metabolic diseases in adulthood. The aim of the present study was to examine maternal nutrient intakes during early pregnancy. 257 healthy women were recruited from the antenatal clinic at the...

1 Aug 2011

Abstract

The aim of this study was to explore associations between fasting whole blood serotonin levels and anthropometric measures in healthy male and female volunteers (N=68) aged between 20 and 66 years. A fasting (20 ml) venous blood sample for whole blood serotonin was collected, after which body mass index and waist circumference (WC) were measured by DEXA (dual energy x-ray absorptiometry) scan. Data were analysed using the SPSS (Statistical Package for the Social Sciences v 17....

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